Current status and advances in immunotherapy for advanced renal cell carcinoma

doi:10.3760/cma.j.cn371439-20240820-00019

Abstract

Abstract:

Approximately 25% of renal cell carcinoma （RCC） patients are already at an advanced stage at the time of initial diagnosis. Additionally， nearly 30% of patients with localized RCC eventually develop distant metastases even after undergoing radical surgery. Traditional chemotherapy and radiotherapy have shown limited effect on advanced RCC treatment， resulting in poor prognosis， with a 5-year survival rate of only about 8%. In recent years， immunotherapy for RCC has become a significant focus of research. With further research， the treatment options for advanced RCC have become increasingly diverse. The exploration of the current clinical applications and research advancements in immunotherapy for advanced RCC could offer medical evidence for optimizing treatment strategies for advanced RCC patients.

Key words: Carcinoma， renal cell, Immunotherapy, Immune checkpoint inhibitor

Chen Ruyan, Fu Zhenming. Current status and advances in immunotherapy for advanced renal cell carcinoma[J]. Journal of International Oncology, 2025, 52(2): 124-128.

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