Cancer-related anorexia refers to the loss or reduction of appetite caused by cancer itself and/or anticancer treatments. This condition encompasses a spectrum of symptoms, including anorexia, nausea, gustatory alteration, early satiety or dysphagia, etc. Cancer-related anorexia not only affects the nutritional status of patients, but is also closely associated with severe adverse outcomes, such as reduced survival, decreased compliance with anti-tumor treatment, increased treatment-related side effects, and diminished quality of life. Despite its widespread prevalence among patients and the urgency of its prevention and treatment, the understanding and management of both doctors and patients need to be further deepened and improved. Recognizing these challenges, Chinese Society of Clinical Oncology-Supportive Care and Rehabilitation Committee convened a panel of experts across relevant fields in China to summarize the screening and diagnosis criteria of cancer-related anorexia based on the current status of clinical practice and the existing research evidence, and to systematically propose a comprehensive management strategy. This consensus will become an important reference for clinicians in the diagnosis and treatment of cancer-related anorexia, which can better standardize the diagnosis and treatment measures for cancer-related anorexia, achieve active screening, early intervention and standardized treatment, so as to benefit more patients.