Progress of clinical application of circulating tumor cells in lung cancer

doi:10.3760/cma.j.cn371439-20240607-00018

Abstract

Abstract:

Lung cancer is the cancer with the highest incidence of morbidity and mortality in the world， and the number of lung cancer cases in China is also increasing year by year， which seriously threatens the life and health of human beings. Circulating tumor cells （CTCs） refer to the tumor cell that falls off from primary tumor tissue or metastatic focus into the peripheral blood， which is the key to tumor metastasis. Currently， there are various methods for CTCs testing， each with its own advantages and disadvantages. In recent years， there have been numerous studies on the application of CTCs in lung cancer around the world. Further exploration of the progress of clinical application of CTCs in lung cancer can provide a new basis for the role of CTCs in early diagnosis， efficacy assessment and prognostic monitoring of lung cancer.

Key words: Neoplastic cells， circulating, Lung neoplasms, Liquid biopsy, Diagnosis, Prognosis

Chen Danlei, Deng Junjun, Li Miao. Progress of clinical application of circulating tumor cells in lung cancer[J]. Journal of International Oncology, 2025, 52(2): 119-123.

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