Journal of International Oncology ›› 2021, Vol. 48 ›› Issue (6): 381-384.doi: 10.3760/cma.j.cn371439-20200622-00074

• Reviews • Previous Articles    

Immune, targeted therapy and related issues of relapsed/refractory multiple myeloma

Sun Ruijie1, Shan Ningning1,2()   

  1. 1Department of Hematology, Shandong Provincial Hospital Affiliated to Shandong University, Shandong Provincial Hospital, Jinan 250021, China
    2Department of Hematology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Shandong Provincial Hospital, Jinan 250021, China
  • Received:2020-06-22 Revised:2020-07-22 Online:2021-06-08 Published:2021-06-24
  • Contact: Shan Ningning E-mail:snning@126.com
  • Supported by:
    Science and Technology Plan of Jinan of China(201907021)

Abstract:

The new immune and targeted therapy medicines of multiple myeloma and recurrence of refractory multiple myeloma mainly include immunomodulatory drugs, proteasome inhibitors, monoclonal antibody, immune monitoring point inhibitors, histone deacetylase and chimeric antigen receptor. Although the emergence of new drugs and the application of autologous hematopoietic stem cell transplantation have significantly improved the prognosis of patients, more effective treatment methods and treatment strategies are still required to deal with the adverse reactions and the condition of recurrence during treatment.

Key words: Multiple myeloma, Molecular targeted therapy, Immunotherapy