国际肿瘤学杂志 ›› 2021, Vol. 48 ›› Issue (7): 424-428.doi: 10.3760/cma.j.cn371439-20201216-00081

• 综述 • 上一篇    下一篇

肿瘤细胞对肿瘤微环境的影响

周邓婧1, 姚颐1,2(), 宋启斌1,2(), 吴彬1, 肖梦霞1, 杨思琦1   

  1. 1武汉大学人民医院肿瘤中心 430060
    2湖北省肿瘤精准医学研究中心,武汉 430200
  • 收稿日期:2020-12-16 修回日期:2021-01-10 出版日期:2021-07-08 发布日期:2021-07-26
  • 通讯作者: 姚颐,宋启斌 E-mail:yaoyi2018@whu.edu.cn;qibinsong@163.com
  • 基金资助:
    吴阶平医学基金会临床科研专项资助基金(320.6750.19094-18)

Effect of tumor cells on tumor microenvironment

Zhou Dengjing1, Yao Yi1,2(), Song Qibin1,2(), Wu Bin1, Xiao Mengxia1, Yang Siqi1   

  1. 1Cancer Center, Renmin Hospital of Wuhan University, Wuhan 430060, China
    2Hubei Provincial Research Center for Precision Medicine of Cancer, Wuhan 430200, China
  • Received:2020-12-16 Revised:2021-01-10 Online:2021-07-08 Published:2021-07-26
  • Contact: Yao Yi,Song Qibin E-mail:yaoyi2018@whu.edu.cn;qibinsong@163.com
  • Supported by:
    Wujieping Medical Foundation Clinical Research Special Fund(320.6750.19094-18)

摘要:

肿瘤细胞与肿瘤微环境(TME)关系密切。目前已知多种因素会改变TME影响肿瘤发展,然而TME的改变也离不开肿瘤细胞。越来越多的研究证实,调节TME是抗肿瘤治疗的关键,因此了解肿瘤细胞对TME的影响十分重要。

关键词: 肿瘤微环境, 肿瘤细胞

Abstract:

Tumor cells and tumor microenvironment (TME) are closely related. It is known that many factors will change the TME, then affect tumor development, however the change of TME is also inseparable from tumor cells. More and more studies have confirmed that the regulation of TME is the key to anti-tumor therapy. Therefore, it is critical to understand the effect of tumor cells on TME.

Key words: Tumor microenvironment, Neoplastic cells