国际肿瘤学杂志 ›› 2024, Vol. 51 ›› Issue (2): 105-108.doi: 10.3760/cma.j.cn371439-20230621-00015

• 综述 • 上一篇    下一篇

液体活检技术在食管鳞状细胞癌中的研究进展

刘博翰, 黄俊星()   

  1. 南京医科大学附属泰州人民医院肿瘤科,泰州 225300
    大连医科大学临床医学系,大连 116000
  • 收稿日期:2023-06-21 修回日期:2023-11-06 出版日期:2024-02-08 发布日期:2024-04-03
  • 通讯作者: 黄俊星,Email:hjxtz@sina.cn
  • 基金资助:
    江苏省卫生健康委科研课题(BJ20012);泰州市科学技术局2020年社会发展指令性计划(TS202001);江苏省医学创新团队项目(CXTDA2017042)

Research progress of liquid biopsy technology in esophageal squamous cell carcinoma

Liu Bohan, Huang Junxing()   

  1. Department of Oncology,Affiliated Taizhou People's Hospital of Nanjing Medical University,Taizhou 225300,China
    Department of Clinical Medicine,Dalian Medical University,Dalian 116000,China
  • Received:2023-06-21 Revised:2023-11-06 Online:2024-02-08 Published:2024-04-03
  • Contact: Huang Junxing,Email:hjxtz@sina.cn
  • Supported by:
    Jiangsu Provincial Health Commission Research Project(BJ20012);Taizhou Science and Technology Bureau 2020 Social Development Mandatory Plan Project(TS202001);Medical Innovation Team Project of Jiangsu Province of China(CXTDA2017042)

摘要:

近年来,随着生物技术的不断发展,液体活检技术在肿瘤领域的研究逐渐成为研究的热点,其作为一种非侵入性的诊断方法,相较于传统手段具有很大的优势。液体活检技术显示出精准、方便、无创、安全等特点,在食管鳞状细胞癌的早期诊断、治疗及预后评估方面具有越来越重要的临床意义。

关键词: 食道鳞癌, 肿瘤细胞, 循环, 外泌体, 循环肿瘤DNA, 循环肿瘤RNA

Abstract:

In recent years,with the continuous development of biotechnology,liquid biopsy techno-logy has gradually become a research hotspot in the field of tumor research. As a non-invasive diagnostic method,liquid biopsy has great advantages compared with traditional methods. The liquid biopsy technology is precise,convenient,non-invasive and safe,and has an increasingly important clinical significance in the early diagnosis,treatment and prognosis assessment of esophageal squamous cell carcinoma.

Key words: Esophageal squamous cell carcinoma, Neoplastic cells, circulating, Exosomes, Circula-ting tumor DNA, Circulating tumor RNA