Research progress on tumor microenvironment and immune combination therapy of MSS colorectal cancer

doi:10.3760/cma.j.cn371439-20221213-00037

Abstract

Abstract:

In recent years， immunotherapy， especially immune checkpoint inhibitors， has shown obvious advantages in prolonging the survival of patients with advanced tumors， and the tumor microenvironment is one of the important factors affecting the efficacy of immunity. Patients with microsatellite-stable colorectal cancer exhibit immune responses in combination with immune checkpoint inhibitor therapy. In-depth exploration of the tumor microenvironment characteristics of microsatellite-stable colorectal cancer and the application of combined immune checkpoint inhibitor therapy can provide new ideas and directions for colorectal cancer immunotherapy.

Key words: Colorectal neoplasms, Tumor microenvironment, Immunotherapy, Microsatellite stable

Xu Liangfu, Li Yuanfei. Research progress on tumor microenvironment and immune combination therapy of MSS colorectal cancer[J]. Journal of International Oncology, 2023, 50(3): 186-190.

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