Journal of International Oncology ›› 2024, Vol. 51 ›› Issue (1): 55-58.doi: 10.3760/cma.j.cn371439-20230627-00007

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Breast microbiota and breast cancer: present and future

Gu Huayan, Zhu Teng, Guo Guilong()   

  1. Department of Breast Surgery, First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China
  • Received:2023-06-27 Revised:2023-08-20 Online:2024-01-08 Published:2024-01-23
  • Contact: Guo Guilong E-mail:guoguilong@sina.com

Abstract:

In recent years, studies have found that breast microbiota differs between breast cancer tissue and normal breast tissue. Breast microbiota is closely related to the occurrence and development of breast cancer, and its mechanism includes affecting estrogen levels, lipid metabolism, immune regulation, and inflammatory response. Adjusting diet, rational use of antibiotics and oral probiotics can regulate breast microbiota, which is a new direction for the prevention and treatment of breast cancer.

Key words: Breast neoplasms, Microbiota, Tumor microenvironment, Estrogens