Journal of International Oncology ›› 2021, Vol. 48 ›› Issue (7): 441-444.doi: 10.3760/cma.j.cn371439-20201005-00085

• Gut Microbiota and Tumor • Previous Articles     Next Articles

Research status of fecal detection for colorectal cancer markers

Wang Yang, Liu Qian, Long Hui, Wu Qingming()   

  1. Department of Gastroenterology, Tianyou Hospital Affiliated to Wuhan University of Science and Technology, Wuhan 430064, China
  • Received:2020-10-05 Revised:2021-03-09 Online:2021-07-08 Published:2021-07-26
  • Contact: Wu Qingming E-mail:wuhe9224@sina.com

Abstract:

There are four methods for fecal detection of colorectal cancer (CRC) markers: fecal occult blood test, fecal DNA test, fecal microRNA test, and fecal fusobacterium nucleatum (Fn) test. Fecal immunochemical test has been recommended by experts at home and abroad as the first choice for CRC screening. Fecal DNA test, due to its high price, has not yet been screened for large samples of people in China, so it is recommended as the second level of CRC screening. Fecal microRNA detection has been paid more and more attention by researchers. In recent years, the detection of fecal microbial markers has become more and more popular, especially fecal Fn detection, which is expected to become a microbial indicator for CRC screening.

Key words: Colorectal neoplasms, Feces, MicroRNAs, Fusobacterium nucleatum, Fecal occult blood test