Journal of International Oncology ›› 2021, Vol. 48 ›› Issue (7): 436-440.doi: 10.3760/cma.j.cn371439-20201019-00084

• Gut Microbiota and Tumor • Previous Articles     Next Articles

Application of gut microbiome in the diagnosis and treatment of tumor

An Jianghong1, Qian Shen2, Luo Pu1, Tan Xiaohua1()   

  1. 1Department of Oncology and Hematology, Third People's Hospital of Shenzhen, Second Affiliated Hospital, Southern University of Science and Technology, Shenzhen 518000, China
    2Department of Respiratory and Critical Care Medicine, First Medical Center, PLA General Hospital, Beijing 100853, China
  • Received:2020-10-19 Revised:2020-11-05 Online:2021-07-08 Published:2021-07-26
  • Contact: Tan Xiaohua E-mail:xiaohua_t@hotmail.com

Abstract:

Gut microbiome is closely related to human health. Changes in intestinal microbial composition promote the development of tumors. Specific intestinal microorganisms and their metabolites regulate host physiological functions and tumor microenvironment, significantly affecting the anti-cancer treatment response and its adverse events. Strategies targeting gut microbiome have shown promising prospects in diagnosis and treatment of cancer.

Key words: Gut microbiome, Tumor microenvironment, Immunotherapy