Abstract: Women diagnosed with breast cancer have a significantly higher risk of developing contralateral breast carcinoma. When the dignosis of “bilateral breast cancer (BBC)” is established, the challenges for the doctors are to determine contralateral breast carcinoma is metastasis or primary lesions. The pathological type, receptor status, biological behavior and the prognosis of bilateral breast cancer are the issues have to be considered. On the other hand, we discuss which type of breast cancer trend to be bilateral breast cancer, thus more effective follow-up and preventive procedures would be applied on the patients with bilateral breast cancer to improve their quality of life and the curative rate.

Key words: Breast neoplasms, Pathology, clinical, Therapy, Bilateral breast cancer