Journal of International Oncology ›› 2017, Vol. 44 ›› Issue (2): 118-121.doi: 10.3760/cma.j.issn.1673422X.2017.02.010

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Research progress of Rab10 in tumor

JIA  Wei, WANG  Wei   

  1. Department of Medical Oncology, Anhui Provincial Hospital, Anhui Medical University, Hefei 230001, China
  • Online:2017-02-08 Published:2017-01-04
  • Contact: Wang Wei E-mail:whouwei@gmail.com
  • Supported by:

    National Natural Science Foundation of China (81201906)

Abstract: As a member of GTPase Rab family, Rab10 protein is not only involved in vesicle formation, transport, anchoring and fusion process, but also affects the occurrence and development of tumors. Research about the mechanisms of Rab10 in intracellular vesicle transport and tumor may provide a potential target and new idea for the anticancer therapy.

Key words: rab GTPbinding proteins, Neoplasms, Transport vesicles, Molecular targeted therapy