Exosomal microRNAs and their roles in tumors

doi:10.3760/cma.j.issn.1673-422X.2017.06.009

Journal of International Oncology ›› 2017, Vol. 44 ›› Issue (6): 438-.doi: 10.3760/cma.j.issn.1673-422X.2017.06.009

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Exosomal microRNAs and their roles in tumors

Zhu Dongwei, Wang Yungang, Xia Xueli, Wang Shengjun

Institute of Immunology, Jiangsu University Medical College; Key Laboratory of Laboratory Medicine of Jiangsu Province, Zhenjiang 212013, China

Online:2017-06-08 Published:2017-06-16
Contact: Wang Shengjun E-mail:sjwjsu@aliyun.com
Supported by:
National Natural Science Foundation of China (31470881); University Students Innovation and Entrepreneurship Program of Jiangsu Province of China (201610299053Y); Research and Innovation Program for Graduate Student of Jiangsu Province of China (KYLX16_0920)

Abstract

Abstract: Exosomes contain many components including variety kinds of lipids, proteins, microRNAs (miRNAs) and so on. They can transport their loaded substances to the recipient cells and play a role of biology. Exosomal miRNAs play important roles in the occurrence and development of tumors, and they are closely related to the tumor growth, metastasis, drug resistance and immune regulation. Exosomes and exosomal miRNAs can be served as reference indexes for tumor metastasis and prognosis, which provide new targets for tumor therapy.

Key words: Neoplasms, MicroRNAs, Exosomes

Zhu Dongwei, Wang Yungang, Xia Xueli, Wang Shengjun. Exosomal microRNAs and their roles in tumors[J]. Journal of International Oncology, 2017, 44(6): 438-.

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Exosomal microRNAs and their roles in tumors

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