Journal of International Oncology ›› 2017, Vol. 44 ›› Issue (1): 75-77.doi: 10.3760/cma.j.issn.1673-422X.2017.01.020

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The role of microRNA-32 in hepatocarcinoma

Jiang Xiaojia, Li Shengmian   

  1. Department of Gastroenterology, Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China
  • Online:2017-01-08 Published:2016-12-07
  • Contact: Li Shengmian, Email: shengmianli2013@163.com E-mail:shengmianli2013@163.com

Abstract: MicroRNAs (miRNA) play an important role in a variety of cellular biology processes, and participate in the occurrence and development of a variety of diseases including hepatocellular carcinoma (HCC). In recent years, miR-32 has been shown to be aberrantly expressed in many tumor tissues. miR-32 is up-regulated in HCC and plays an oncogene role in regulating the cell cycle, apoptosis, invasion, metastasis and so on. MiR-32 maybe a potential target for HCC therapy.

Key words: Liver neoplasms, MicroRNAs, MicroRNA-32