Role of tertiary lymphoid structures in tumor immune microenvironment regulation and anti-tumor therapy

doi:10.3760/cma.j.cn371439-20221121-00033

Abstract

Abstract:

Tertiary lymphoid structures （TLSs） is important channel for tumor immune cell infiltration. The existence of tumor TLSs is not only related to the prognosis of patients， but also to the efficacy of a variety of anti-tumor therapies. To explore the function and immunomodulatory mechanism of TLSs and its potential value as a tumor prognostic biomarker in comprehensive anti-tumor therapy will provide new ideas for follow-up research.

Key words: Tertiary lymphoid structures, Tumor microenvironment, Treatment outcome

Cao Mengqing, Xu Zhiyong, Shi Yuting, Wang Kai. Role of tertiary lymphoid structures in tumor immune microenvironment regulation and anti-tumor therapy[J]. Journal of International Oncology, 2023, 50(3): 169-173.

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