Journal of International Oncology ›› 2020, Vol. 47 ›› Issue (12): 765-768.doi: 10.3760/cma.j.cn371439-20200214-00117

• Reviews • Previous Articles    

Recent advances in immunotherapy for relapsed or refractory multiple myeloma

Hou Yuanmei1(), Li Junpeng2   

  1. 1Ultrasound Diagnostic Center, Hwa Mei Hospital, University of Chinese Academy of Sciences (Ningbo No.2 Hospital), Ningbo 315010, China
    2Department of Cardiovascular Surgery, Hwa Mei Hospital, University of Chinese Academy of Sciences (Ningbo No.2 Hospital), Ningbo 315010, China
  • Received:2020-02-14 Revised:2020-08-19 Online:2020-12-08 Published:2021-01-28
  • Contact: Hou Yuanmei E-mail:1761222033@qq.com

Abstract:

Immunotherapy strategies have shown benefits in the treatment of multiple myeloma (MM), however a certain percentage of patients progress to relapsed or refractory MM. In addition to monoclonal antibodies against antigens on tumor cells, the latest immunotherapy strategies include bispecific antibodies, immune checkpoint inhibitors, chimeric antigen receptor modified T cell and Bruton tyrosine kinase inhibitors, which provide more possibilities for immunotherapy of relapsed or refractory MM.

Key words: Multiple myeloma, Antibodies, monoclonal, Immunosuppressive agents, Antibodies drug conjugates