三维细胞模型在肿瘤实验中的应用

doi:10.3760/cma.j.issn.1673-422X.2015.07.015

摘要/Abstract

摘要： 三维细胞培养是目前公认的能较好模拟体内肿瘤细胞微环境及细胞间相互作用的体外模型。与传统二维细胞培养相比，它在观察肿瘤细胞生物学行为、耐药及放射不敏感、体内基因表达等研究中具有明显优势，能为肿瘤基础实验研究提供极具价值的体外模型。

关键词: 肿瘤转移, 细胞培养技术, 肿瘤微环境

Abstract: Threedimensional cell culture is widely recognized as a model in vitro that can better simulate the interaction between tumor cells in vivo and cell microenvironment. Compared with the traditional twodimensional cell culture, it has obvious advantages in the study of the observation of tumor cells biological behavior, tumor resistance, radiation insensitivity, gene expression in vivo and in other aspects of the study. It can provide a valuable model in vitro for experimental study on the basis of tumor.

Key words: Neoplasm metastasis, Cell culture techniques, Tumor microenvironment

冯飞，秦颂兵. 三维细胞模型在肿瘤实验中的应用[J]. 国际肿瘤学杂志, 2015, 42(7): 532-534.

Feng Fei, Qin Songbing. Application of threedimensional cell culture model in cancer research[J]. Journal of International Oncology, 2015, 42(7): 532-534.

参考文献

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