国际肿瘤学杂志 ›› 2024, Vol. 51 ›› Issue (2): 114-118.doi: 10.3760/cma.j.cn371439-20231016-00017

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结直肠癌肝转移组织病理学生长方式研究进展

孙国宝, 杨倩, 庄庆春, 高斌斌, 孙晓刚, 宋伟, 沙丹()   

  1. 山东第一医科大学附属省立医院肿瘤微创科,济南 250021
  • 收稿日期:2023-10-16 修回日期:2024-01-20 出版日期:2024-02-08 发布日期:2024-04-03
  • 通讯作者: 沙丹,Email:shadan@sdfmu.edu.cn
  • 基金资助:
    山东省自然科学基金(ZR2021MH140);济南市临床医学科技创新计划(202019085)

Research progress on the histopathological growth patterns of colorectal liver metastasis

Sun Guobao, Yang Qian, Zhuang Qingchun, Gao Binbin, Sun Xiaogang, Song Wei, Sha Dan()   

  1. Department of Minimally Invasive Treatment of Cancer,Shandong Provincial Hospital Affiliated to Shandong First Medical University,Jinan 250021,China
  • Received:2023-10-16 Revised:2024-01-20 Online:2024-02-08 Published:2024-04-03
  • Contact: Sha Dan,Email:shadan@sdfmu.edu.cn
  • Supported by:
    Natural Science Foundation of Shandong Province of China(ZR2021MH140);Science and Technology Innovation Development Program of Jinan of Shandong Province(202019085)

摘要:

结直肠癌(CRC)肝转移瘤的不同组织病理学生长方式(HGP)反映了肿瘤与宿主之间复杂而多变的相互作用。探讨HGP肿瘤血管化特点和免疫特征、HGP与抗肿瘤治疗疗效的关系以及HGP预测方法对于制定最佳治疗方案、评估患者预后和监测疾病进展具有潜在的临床应用价值。

关键词: 结直肠肿瘤, 肿瘤转移, 肝肿瘤, 组织病理学生长方式

Abstract:

The histopathological growth patterns (HGPs)of colorectal cancer (CRC)liver metastasis reflect the complicated and varied interactions between tumor cells and host microenvironment. Exploring the tumor vascular and immunological features of HGPs,the relationship between HGPs and anti-tumor treatment efficacy,and HGPs prediction methods may have potential clinical aplication value for making optimal treatment strategies,evaluating patients' prognosis,and monitoring disease progression.

Key words: Colorectal neoplasms, Neoplasm metastasis, Liver neoplasms, Histopathological growth patterns