Journal of International Oncology ›› 2015, Vol. 42 ›› Issue (11): 866-868.doi: 10.3760/cma.j.issn.1673422X.2015.11.019

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Biological research of liver cancer stem cells

Chen Feiyu, Zhang Anna, Ren Junguo.   

  1. Graduate School of Beijing University of Chinese Medicine &  Institute of Basic Medical Sciences of Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China
  • Online:2015-11-08 Published:2015-09-30
  • Contact: Ren Junguo E-mail:reek2003@163.com

Abstract: Liver cancer stem cell plays an important role in hepatocarcinoma occurrence and metastasis.Presently,the two theories about the source of liver cancer stem cells are mature hepatocytes′ dedifferentiation and hepatic stem cells′ blocked differentiation.Side population cell sorting and different surface antigen labeling are general sorting methods of hepatocarcinoma stem cells.Targeting the liver cancer stem cells population provides an effective way to the treatments of liver neoplasms.

Key words: Liver neoplasms, Neoplastic stem cells, Biology