Journal of International Oncology ›› 2014, Vol. 41 ›› Issue (6): 463-466.doi: 10.3760/cma.j.issn.1673422X.2014.06.019

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MicroRNA and diffuse large Bcell lymphoma

Wang Xinyuan*, Yang Xigui, Jiang Chao   

  1. *School of Medical and Life Sciences, Shandong Academy of Medical Sciences, Jinan University; Department of Medical Oncology, Shandong Cancer Hospital, Jinan 250117, China
  • Online:2014-06-08 Published:2014-05-08
  • Contact: Yang Xigui E-mail:zlysxgy@126.com

Abstract: MicroRNA (miRNA) is a kind of naturally occurring short noncoding small molecular RNA, which regulates gene expression at the posttranscriptional level through its sequence complementation with target mRNAs. Researches have shown that different malignant tumors, including diffuse large B cell lymphoma, have specific miRNA expression profiles. Therefore, miRNAs expression level of specimens of body fluids and tissues is expected to be the new indicator for assessing diffuse large B cell lymphoma.

Key words: MicroRNAs, Lymphoma, large Bcell, diffuse