Abstract: The oligometastasic stage is an intermediate state with mild biological invasion, in which spread may be limited to specific organs and not occour polymetastases. The number of metastatic tumors is limited less than five. Local therapy such as radiotherapy, surgery and radiofrequency ablation for the relapsed sites could thus improve patient’s survival. The expression of miR-200 family characterizes oligometastasis(es). Correct understanding and familiarization with treatment of oligometastasis may change the traditional therapeutic strategy of advanced tumors，and some advanced cancer patients may achieve curable results.

Key words: Neoplasms, Radiotherapy, Surgical procedures, operative, Oligometastasis