Abstract: The application of ¹⁸F-FDG PET-CT in the diagnosis and treatment of nasopharyngeal carcinoma includes early diagnosis, clinical staging, contouring target volume, predicting the sensitivity of tumors to radiotherapy and effect evaluation, and monitoring the residual and recurrence. However, ¹⁸F-FDG uptake of tumor cells is under the influence of various factors, so false positive and false negative are unavoidable. Therefore it is need to develop more specific tracer agent in order to improve the accuracy of diagnosis and treatment, as well as to carry out multicenter clinical trial to identify the correlation of standardized uptake value （SUV） and radiation target volume.

Key words: Nasopharyngeal neoplasms, Radiotherapy, PET-CT