Abstract: Gastric cancer can spread to the liver through hematogenous metastasis, lymphatic metastasis and serosal invasion of primary tumor. The occurrence of gastric cancer with liver metastasis is only second to the occurrence of peritoneal metastasis. Liver metastasis is one of the main distant metastasis of gastric cancer, and is a major cause of cancer-related death. The treatment of gastric cancer with liver metastasis still remains controversial. The optimal treatment strategies should be based on the clinicopathological characteristics of each patients and evidence-based medicine, and the individualized plan should be set through multidisciplinary team discussions. Before the more results of prospective studies released, multidisciplinary treatment is the main method, and the appropriate patients should be cautiously choosed for surgery.

Key words: Stomach neoplasms, Neoplasm metastasis, Therapy