Abstract: Induced pluripotent stem cells (iPSCs) are derived from differentiated somatic cells through reprogramming in vitro. Similarly to embryonic stem cells (ESCs), iPSC have the ability of unlimited self-renewal and multiple differentiation potential. But they are without the constraints of immunology and ethics and acquire conveniently. Patient-specific iPSC provide an invaluable resource for disease modeling, drug discovery, regenerative therapy, immune therapy and cellular delivery vehicle in cancer therapy. Nowadays, the application of iPSC technology has made some progress in the treatment of tumors.

Key words: Cell differentation, Neoplasms, Induced pluripotent stem cells