Progress in imaging evaluation of lateral lymph node metastasis in rectal cancer

doi:10.3760/cma.j.cn371439-20230217-00049

Abstract

Abstract:

Lateral drainage is an important way for the middle and lower rectum. There are still disputes between Eastern and Western scholars regarding the treatment strategy of lateral lymph node metastasis. It is difficult to diagnose lateral lymph node metastasis by pathologic examination before surgery. MRI is the main method for diagnosis of lateral lymph node metastasis in rectal cancer. The diagnostic criteria for patients before and after neoadjuvant treatment are slightly different. CT， PET/CT and radiomics also have certain advantages in the diagnosis of lateral lymph node metastasis. If necessary， the combination of multiple methods can help in the diagnosis of lateral lymph node metastasis.

Key words: Rectal neoplasms, Lymphatic metastasis, Magnetic resonance imaging, Tomography

Zeng Liwu, Du Yuqiang, Zhang Peng, Tao Kaixiong. Progress in imaging evaluation of lateral lymph node metastasis in rectal cancer[J]. Journal of International Oncology, 2023, 50(4): 248-251.

References 33

[1]	Sung H, Ferlay J, Siegel RL, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer J Clin, 2021, 71(3): 209-249. DOI: 10.3322/caac.21660. doi: 10.3322/caac.21660
[2]	Japanese Society for Cancer of the Colon and Rectum. Japanese classification of colorectal, appendiceal, and anal carcinoma: the 3d English edition [secondary publication][J]. J Anus Rectum Colon, 2019, 3(4): 175-195. DOI: 10.23922/jarc.2019-018. doi: 10.23922/jarc.2019-018 pmid: 31768468
[3]	Hiyoshi Y, Miyamoto Y, Kiyozumi Y, et al. Risk factors and prognostic significance of lateral pelvic lymph node metastasis in advanced rectal cancer[J]. Int J Clin Oncol, 2020, 25(1): 110-117. DOI: 10.1007/s10147-019-01523-w. doi: 10.1007/s10147-019-01523-w pmid: 31407167
[4]	陈致奋. AJCC与JSCCR对直肠癌盆腔侧方淋巴结定义演变的解读[J]. 中国普通外科杂志, 2019, 28(4): 387-391. DOI: 10.7659/j.issn.1005-6947.2019.04.002. doi: 10.7659/j.issn.1005-6947.2019.04.002
[5]	Hajibandeh S, Hajibandeh S, Matthews J, et al. Meta-analysis of survival and functional outcomes after total mesorectal excision with or without lateral pelvic lymph node dissection in rectal cancer surgery[J]. Surgery, 2020, 168(3): 486-496. DOI: 10.1016/j.surg.2020.04.063. doi: 10.1016/j.surg.2020.04.063
[6]	Benson AB, Venook AP, Al-Hawary MM, et al. Rectal cancer, version 2.2022, NCCN clinical practice guidelines in oncology[J]. J Natl Compr Canc Netw, 2022, 20(10): 1139-1167. DOI: 10.6004/jnccn.2022.0051. doi: 10.6004/jnccn.2022.0051
[7]	Zhou S, Tang J, Liang J, et al. Effective dissecting range and prognostic significance of lateral pelvic lymph node dissection for middle-low rectal cancer patients with lateral pelvic lymph node metastasis: results of a large multicenter lateral node collaborative group in China[J]. Front Oncol, 2022, 12: 916285. DOI: 10.3389/fonc.2022.916285. doi: 10.3389/fonc.2022.916285
[8]	Hashiguchi Y, Muro K, Saito Y, et al. Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2019 for the treatment of colorectal cancer[J]. Int J Clin Oncol, 2020, 25(1): 1-42. DOI: 10.1007/s10147-019-01485-z. doi: 10.1007/s10147-019-01485-z pmid: 31203527
[9]	Hoshino N, Murakami K, Hida K, et al. Diagnostic accuracy of magnetic resonance imaging and computed tomography for lateral lymph node metastasis in rectal cancer: a systematic review and meta-analysis[J]. Int J Clin Oncol, 2019, 24(1): 46-52. DOI: 10.1007/s10147-018-1349-5. doi: 10.1007/s10147-018-1349-5 pmid: 30259217
[10]	Ishihara S, Kawai K, Tanaka T, et al. Correlations between the sizes of lateral pelvic lymph nodes and metastases in rectal cancer patients treated with preoperative chemoradiotherapy[J]. ANZ J Surg, 2018, 88(12): 1306-1310. DOI: 10.1111/ans.14717. doi: 10.1111/ans.14717 pmid: 29974631
[11]	Kim MJ, Hur BY, Lee ES, et al. Prediction of lateral pelvic lymph node metastasis in patients with locally advanced rectal cancer with preoperative chemoradiotherapy: focus on MR imaging findings[J]. PLoS One, 2018, 13(4): e0195815. DOI: 10.1371/journal.pone.0195815. doi: 10.1371/journal.pone.0195815
[12]	Park BK, Lee SJ, Hur BY, et al. Feasibility of selective lateral node dissection based on magnetic resonance imaging in rectal cancer after preoperative chemoradiotherapy[J]. J Surg Res, 2018, 232: 227-233. DOI: 10.1016/j.jss.2018.05.047. doi: S0022-4804(18)30351-2 pmid: 30463722
[13]	Sekido Y, Nishimura J, Fujino S, et al. Predicting lateral pelvic lymph node metastasis based on magnetic resonance imaging before and after neoadjuvant chemotherapy for patients with locally advanced lower rectal cancer[J]. Surg Today, 2020, 50(3): 292-297. DOI: 10.1007/s00595-019-01886-7. doi: 10.1007/s00595-019-01886-7 pmid: 31595366
[14]	Komori K, Fujita S, Mizusawa J, et al. Predictive factors of pathological lateral pelvic lymph node metastasis in patients without clinical lateral pelvic lymph node metastasis (clinical stage Ⅱ/Ⅲ): the analysis of data from the clinical trial (JCOG0212)[J]. Eur J Surg Oncol, 2019, 45(3): 336-340. DOI: 10.1016/j.ejso.2018.11.016. doi: S0748-7983(18)32014-6 pmid: 30477950
[15]	Zhou S, Jiang Y, Pei W, et al. Neoadjuvant chemoradiotherapy followed by lateral pelvic lymph node dissection for rectal cancer patients: a retrospective study of its safety and indications[J]. J Surg Oncol, 2021, 124(3): 354-360. DOI: 10.1002/jso.26509. doi: 10.1002/jso.26509 pmid: 33882149
[16]	Dev K, Veerenderkumar KV, Krishnamurthy S. Incidence and predictive model for lateral pelvic lymph node metastasis in lower rectal cancer[J]. Indian J Surg Oncol, 2018, 9(2): 150-156. DOI: 10.1007/s13193-017-0719-1. doi: 10.1007/s13193-017-0719-1
[17]	Ishibe A, Ota M, Watanabe J, et al. Prediction of lateral pelvic lymph-node metastasis in low rectal cancer by magnetic resonance imaging[J]. World J Surg, 2016, 40(4): 995-1001. DOI: 10.1007/s00268-015-3299-7. doi: 10.1007/s00268-015-3299-7 pmid: 26541864
[18]	Ishizaki T, Katsumata K, Enomoto M, et al. Predictors of lateral pelvic lymph node metastasis in advanced low rectal cancer treated with neoadjuvant chemotherapy[J]. Anticancer Res, 2022, 42(4): 2113-2121. DOI: 10.21873/anticanres.15693. doi: 10.21873/anticanres.15693 pmid: 35347035
[19]	中国医师协会内镜医师分会腹腔镜外科专业委员会, 中国医师协会结直肠肿瘤专业委员会腹腔镜专业委员会, 中华医学会外科学分会结直肠外科学组. 中国直肠癌侧方淋巴结转移诊疗专家共识(2019版)[J]. 中华胃肠外科杂志, 2019, 22(10): 901-912. DOI: 10.3760/cma.j.issn.1671-0274.2019.10.001. doi: 10.3760/cma.j.issn.1671-0274.2019.10.001
[20]	Peacock O, Manisundaram N, Dibrito SR, et al. Magnetic resonance imaging directed surgical decision making for lateral pelvic lymph node dissection in rectal cancer after total neoadjuvant therapy (TNT)[J]. Ann Surg, 2022, 276(4): 654-664. DOI: 10.1097/SLA.0000000000005589. doi: 10.1097/SLA.0000000000005589
[21]	Abe T, Yasui M, Imamura H, et al. Combination of extramural venous invasion and lateral lymph node size detected with magnetic resonance imaging is a reliable biomarker for lateral lymph node metastasis in patients with rectal cancer[J]. World J Surg Oncol, 2022, 20(1): 5. DOI: 10.1186/s12957-021-02464-3. doi: 10.1186/s12957-021-02464-3 pmid: 34986842
[22]	陆海迪, 沈浮, 陆建平, 等. 基于磁共振高分辨T2WI影像组学预测直肠癌新辅助治疗后病理完全反应的研究[J]. 国际肿瘤学杂志, 2020, 47(10): 593-597. DOI: 10.3760/cma.j.cn371439-20200527-00084. doi: 10.3760/cma.j.cn371439-20200527-00084
[23]	Malakorn S, Yang Y, Bednarski BK, et al. Who should get lateral pelvic lymph node dissection after neoadjuvant chemoradiation?[J]. Dis Colon Rectum, 2019, 62(10): 1158-1166. DOI: 10.1097/DCR.0000000000001465. doi: 10.1097/DCR.0000000000001465 pmid: 31490825
[24]	Schaap DP, Boogerd LSF, Konishi T, et al. Rectal cancer lateral lymph nodes: multicentre study of the impact of obturator and internal iliac nodes on oncological outcomes[J]. Br J Surg, 2021, 108(2): 205-213. DOI: 10.1093/bjs/znaa009. doi: 10.1093/bjs/znaa009 pmid: 33711144
[25]	Kawai K, Shiratori H, Hata K, et al. Optimal size criteria for lateral lymph node dissection after neoadjuvant chemoradiotherapy for rectal cancer[J]. Dis Colon Rectum, 2021, 64(3): 274-283. DOI: 10.1097/DCR.0000000000001866. doi: 10.1097/DCR.0000000000001866 pmid: 33395141
[26]	Sato K, Morohashi H, Tsushima F, et al. Dual energy CT is useful for the prediction of mesenteric and lateral pelvic lymph node metastasis in rectal cancer[J]. Mol Clin Oncol, 2019, 10(6): 625-630. DOI: 10.3892/mco.2019.1834. doi: 10.3892/mco.2019.1834 pmid: 31031979
[27]	Yukimoto R, Uemura M, Tsuboyama T, et al. Efficacy of positron emission tomography in diagnosis of lateral lymph node metastases in patients with rectal cancer: a retrospective study[J]. BMC Cancer, 2021, 21(1): 520. DOI: 10.1186/s12885-021-08278-6. doi: 10.1186/s12885-021-08278-6 pmid: 33962569
[28]	Amano K, Fukuchi M, Kumamoto K, et al. Pre-operative evaluation of lateral pelvic lymph node metastasis in lower rectal cancer: comparison of three different imaging modalities[J]. J Anus Rectum Colon, 2020, 4(1): 34-40. DOI: 10.23922/jarc.2019-022. doi: 10.23922/jarc.2019-022 pmid: 32002474
[29]	王铮, 肖国有, 赖少侣, 等. ¹⁸F-FDG PET/CT联合MRI评估直肠癌侧方淋巴结转移的应用研究[J]. 中国医疗设备, 2021, 36(7): 89-92, 109. DOI: 10.3969/j.issn.1674-1633.2021.07.020. doi: 10.3969/j.issn.1674-1633.2021.07.020
[30]	Nakanishi R, Akiyoshi T, Toda S, et al. Radiomics approach outperforms diameter criteria for predicting pathological lateral lymph node metastasis after neoadjuvant (chemo)radiotherapy in advanced low rectal cancer[J]. Ann Surg Oncol, 2020, 27(11): 4273-4283. DOI: 10.1245/s10434-020-08974-w. doi: 10.1245/s10434-020-08974-w pmid: 32767224
[31]	Sumii A, Hida K, Sakai Y, et al. Establishment and validation of a nomogram for predicting potential lateral pelvic lymph node metastasis in low rectal cancer[J]. Int J Clin Oncol, 2022, 27(7): 1173-1179. DOI: 10.1007/s10147-022-02157-1. doi: 10.1007/s10147-022-02157-1 pmid: 35415787
[32]	Lahaye MJ, Beets GL, Engelen SM, et al. Locally advanced rectal cancer: MR imaging for restaging after neoadjuvant radiation therapy with concomitant chemotherapy. Part Ⅱ. What are the criteria to predict involved lymph nodes?[J]. Radiology, 2009, 252(1): 81-91. DOI: 10.1148/radiol.2521081364. doi: 10.1148/radiol.2521081364 pmid: 19403848
[33]	Stijns RCH, Philips BWJ, Nagtegaal ID, et al. USPIO-enhanced MRI of lymph nodes in rectal cancer: a node-to-node comparison with histopathology[J]. Eur J Radiol, 2021, 138: 109636. DOI: 10.1016/j.ejrad.2021.109636. doi: 10.1016/j.ejrad.2021.109636