Progress in detection and technology applications of minimal residual disease detection in postoperative early stage non-small cell lung cancers

doi:10.3760/cma.j.cn371439-20220330-00124

Abstract

Abstract:

Surgery is the mainstay of treatment for early lung cancers， but there is still a risk of recurrence and metastasis after surgery. With the advancement of molecular biology and detection methods， detecting the level of postoperative peripheral blood minimal residual disease （MRD） in patients can dynamically monitor recurrence and determine prognosis. Due to the wide variety of MRD detection methods， uneven detection power， lack of uniform standards and prospective study validation， clinical application is still controversial. The further development of MRD detection for early stage cell lung cancer still needs technical progress， standardized detection criteria and credible clinical data.

Key words: Carcinoma， non-small-cell lung, Clinical study, Minimal residual disease, Detection technology

Niu Ruiqi, Liu Pingping, Du Yingying. Progress in detection and technology applications of minimal residual disease detection in postoperative early stage non-small cell lung cancers[J]. Journal of International Oncology, 2022, 49(10): 623-626.

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