Journal of International Oncology ›› 2022, Vol. 49 ›› Issue (10): 619-622.doi: 10.3760/cma.j.cn371439-20220715-00123

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Progress in the treatment of triple negative breast cancer with sacituzumab govitecan

Wang Mengchao, Chen Liwei(), Kong Fanming   

  1. Department of Oncology, First Affiliated Hospital of Tianjin University of Chinese Medicine, National Clinical Research Center of Chinese Acupuncture and Moxibustion, Tianjin 300000, China
  • Received:2022-07-15 Revised:2022-09-11 Online:2022-10-08 Published:2022-12-01
  • Contact: Chen Liwei E-mail:iron9999@126.com
  • Supported by:
    National Key Research and Development Program(2018YFC1707400)

Abstract:

Triple-negative breast cancer is a subtype of invasive breast cancer, accounting for about 15% of all breast cancers. Its clinical treatment is relatively difficult, prone to recurrence and metastasis, with a short median survival and poor prognosis. Sacituzumab govitecan is the first approved antigen-coupled drug targeting trophoblast surface antigen 2 in the world. It has significant clinical efficacy, high safety and less adverse reactions, which brings new hope to the treatment of triple-negative breast cancer.

Key words: Triple negative breast neoplasms, Clinical study, Sacituzumab govitecan