Journal of International Oncology ›› 2019, Vol. 46 ›› Issue (12): 755-759.doi: 10.3760/cma.j.issn.1673-422X.2019.12.010

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Molecular signaling pathways and cancer pain in gastric cancer

Xing Ziyang1, Sun Chunxia2   

  1. 1 Graduate School of Hebei College of Chinese Medicine, Shijiazhuang 050091, China;  2 Second Oncology Department of Affilliated Hospital of Hebei College of Chinese Medicine, Shijiazhuang 050011, China
  • Received:2019-06-24 Revised:2019-07-06 Online:2019-12-08 Published:2019-12-09
  • Contact: Sun Chunxia E-mail:schx1975@163.com
  • Supported by:
    Scientific Research Project of traditional Chinese Medicine in Hebei Province (2016164)

Abstract: The molecular signaling pathways in gastric cancer, such as mitogen-activated protein kinase, phosphoinoinositide 3-kinase/protein kinase B, AMP-activated protein kinase, cyclooxygenase 2/nuclear factor-κB and Wnt/β-catenin pathways are closely related to the occurrence and development of cancer pain. To understand the expression and role of gastric cancer molecular signaling pathway in cancer pain is expected to provide a new idea for the treatment of cancer pain.

Key words: Stomach neoplasms, Cancer pain, Signaling pathway