Journal of International Oncology ›› 2017, Vol. 44 ›› Issue (6): 468-.doi: 10.3760/cma.j.issn.1673-422X.2017.06.017

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Application of antiangiogenesis therapy in the radiotherapy of esophageal cancer

Feng Yue, Yu Jingping, Wang Jianlin   

  1. Department of Radiation Oncology, Changzhou Second People′s Hospital Affiliated to Nanjing Medical University, Changzhou 213003, China
  • Online:2017-06-08 Published:2017-06-16
  • Contact: Yu Jingping E-mail: yujingping@sina.com
  • Supported by:

    Changzhou HighLevel Health Personnel Training Program (2016C2BJ007); Changzhou Scientific and Technological Support Social Development Project (CE20125021, CE20165024); Changzhou Municipal Science and Technology Bureau Basic Research Project (CJ20159050); Jiangsu Province Health Department Guided Research Project (Z201220); Changzhou Health Bureau Major Project (ZD201105)

Abstract: Radiotherapy is the principle method of nonsurgical treatment for esophageal cancer. The 5year survival rate ranges from 20% to 40%. In recent years, the studies have found that antiangiogenesis therapy can not only directly inhibit tumor nutritional intake, but also turn around tumor hypoxia by normalizing tumor vessels so as to enhance the radiosensitivity of tumor cells, which is expected to become an effective way to improve the curative effect of esophageal cancer radiotherapy.

Key words: Esophageal neoplasms, Radiotherapy, Angiogenesis inhibitors