Journal of International Oncology ›› 2017, Vol. 44 ›› Issue (4): 297-299.doi: 10.3760/cma.j.issn.1673-422X.2017.04.015

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The mechanism of RNA interference for hepatocellular carcinoma treatment

Hou Xiaoyun, Chu Yanjun.   

  1. Digestive System Department, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
  • Online:2017-04-08 Published:2017-05-09
  • Contact: Chu Yanjun E-mail:1054900885@qq.com

Abstract: Primary liver cancer is one of the common malignant tumors. However, the efficacy of traditional treatments is not satisfactory. RNA interference is a new treatment method, which develops rapidly in recent years. It has been found that RNA interference can exert the antitumor effect through inhibiting the growth and proliferation of hepatocarcinoma cells, promoting apoptosis, inhibiting the invasion and metastasis of hepatocarcinoma cells, inhibiting angiogenesis and overcoming the resistance to chemotherapy.

Key words: Hepatocellular carcinoma, RNA interferece, Apoptosis, Angiogenesis