Journal of International Oncology ›› 2013, Vol. 40 ›› Issue (2): 141-144.

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Preoperative neoadjuvant therapy for locally advanced rectal cancer

MEI  Lan, XU  Xiang-Ying   

  1. First Department of Radiation Oncology, Third Affiliated Hospital of Harbin Medical University, Herbin 150081, China
  • Online:2013-02-08 Published:2013-01-25
  • Contact: Corresponding author: XU Xiang-ying, E-mail: xuxxyy@sohu.com E-mail:xuxxyy@sohu.com

Abstract: Preoperative radiotherapy combined with chemotherapy and (or) targeted therapy not only reduces the local recurrence of locally advanced rectal cancer and increases the rate of anal preservation and pathologic complete response, but also improves patient compliance. Preoperative neoadjuvant therapy will gradually become the standard treatment for locally advanced rectal cancer.

Key words: Rectal neoplasms, Radiotherapy, Chemotherapy