Journal of International Oncology ›› 2012, Vol. 39 ›› Issue (8): 566-569.

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MicroRNA-related pathways and tumorigenesis and tumor development

LI  Jun, LU  Xin   

  1. Department of Gynecology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China
  • Online:2012-08-29 Published:2012-08-29
  • Contact: LU Xin, E-mail: xinlu98@yahoo.com E-mail:xinlu98@yahoo.com

Abstract: Aberrant microRNA(miRNA) expression has been found in most of human cancers. miRNA-related regulation pathways, including the interaction between miRNA and proteincoding gene and the interaction between miRNA and lncRNA, have been shown correlated with the initiation and progression of human cancers. miRNA might be a therapeutic target in the treatment of malignancies.

Key words: MicroRNAs, Neoplastic processes