Research progress of circadian genes in the occurrence， development and chronotherapy of colorectal cancer

doi:10.3760/cma.j.cn371439-20240528-00009

Abstract

Abstract:

In recent years， studies have found that the abnormal expression of rhythm genes is closely related to the risk of occurrence and the progression of the disease course of colorectal cancer. In addition， chronotherapy based on the circadian rhythm theory has shown certain effects in the clinical treatment of colorectal cancer， but there are still great limitations. Therefore， it is very important to clarify the mechanism of action of rhythm genes in the occurrence and development of colorectal cancer， which may provide a theoretical basis for the clinical application of chronotherapy.

Key words: Circadian rhythm, Colorectal neoplasms, Clock gene

Zhan Haifeng, Tan Zixuan, Wang Wenxue, Geng Jiawei. Research progress of circadian genes in the occurrence， development and chronotherapy of colorectal cancer[J]. Journal of International Oncology, 2025, 52(1): 60-64.

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