Journal of International Oncology ›› 2022, Vol. 49 ›› Issue (2): 116-120.doi: 10.3760/cma.j.cn371439-20210126-00019

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Application of the combination of stereotactic body radiation therapy and immune checkpoint inhibitors in non-small cell lung cancer

Li Ping, Sun Xiaonan()   

  1. Department of Radiation Oncology, Sir Run Run Shaw Hospital of Zhejiang University School of Medicine, Hangzhou 310016, China
  • Received:2021-01-26 Revised:2021-05-15 Online:2022-02-08 Published:2022-03-11
  • Contact: Sun Xiaonan E-mail:sunxiaonan@zju.edu.cn

Abstract:

The major treatments of non-small cell cancer (NSCLC) contain surgery, chemotherapy, radiotherapy, targeted therapy, immunotherapy and the combinations of them. Among them, stereotactic body radiation therapy (SBRT) is applied more and more extensively. Based on the immunoregulatory effects of SBRT, the combination with immune checkpoint inhibitors (ICIs) is used in all stages of NSCLC. This kind of treatment mode needs to be continuously explored to maximize the radio-immunity synergistic effect.

Key words: Carcinoma,non-small-cell lung, Immune checkpoint inhibitors, Stereotactic body radiation therapy