[1] International Agency for Research on Cancer. World cancer report 2008. Lyon: WHO, 2008: 374.
[2] Shahrokni A, Rajebi MR, Saif MW. Toxicity and efficacy of 5fluorouraeil and capecitabine in a patient with TYMS gene polymorphism: a challenge or a dilemma?. Clin Colorectal Cancer, 2009, 8(4): 231234.
[3] Surmont VF, van Meerbeeck JP. Raltitrexed in mesothelioma. Expert Rev Anticancer Ther, 2011, 11(10): 14811490.
[4] Popov I, Carrato A, Sobrero A, et al. Raltitrexed (Tomudex) versus standard leucovorinmodulated bolus 5fluorouracil: results from the randomised phase Ⅲ PanEuropean Trial in Adjuvant Colon Cancer 01 (PETACC1). Eur J cancer, 2008, 44(15): 22042211.
[5] Deboever G, Hitrop N, Cool M, et al. Alternative treatment options in colorectal cancer patients with 5fluorouracil or capecitabineinduced cardiotoxicity. Chin colorectal Cancer, 2013, 12(1): 814.
[6] Viéitez JM, Valladares M, Peláez I, et al. A randomized phase Ⅱ study of raltitrexed and gefitinib versus raltitrexed alone as second line chemotherapy in patients with colorectal cancer. Invest New Drugs, 2011, 29(5): 10381044.
[7] 余嘉文. 雷替曲塞单药二线治疗晚期大肠癌疗效观察. 中国现代药物应用, 2012, 6(4): 1819.
[8] Khouri C, Guiu B, Cercueil JP, et al. Raltitrexed and oxaliplatin hepatic arterial infusion for advanced colorectal cancer: a retrospective study. Anticancer Drugs, 2010, 21(6): 656661.
[9] 王佳蕾, 李进, 秦叔逵, 等. 雷替曲塞或5FU/CF联合奥沙利铂治疗局部晚期或复发转移性结直肠癌多中心、随机、对照Ⅲ期临床试验. 临床肿瘤学杂志, 2012, 17(1): 611.
[10] Gravalos C, Salut A, Sevilla I, et al. A randomized phase Ⅱ study to compare FOLFOX4 versus TOMOX as firstline chemotherapy for advanced colorectal cancer. Clin Transl Oncol, 2012, 14(8): 606612.
[11] Paiva CE, Paiva BS, Garita R, et al. Acute coronary syndrome associated with continuous 5Fluorouracil infusion in a patient with metastatic colorectal cancera case report with a discussion on this clinical dilemma. Gastrointest Cancer, 2009, 40(34): 133137.
[12] Geurs F, Vandewaeter S, Ponette S, et al. Successful and welltolerated second line therapy with cetuximab, irinotecan, and raltitrexed in progressive liver disease due to metastatic colon cancer. J Gastrointest Cancer, 2008, 39(14): 2628.
[13] Aparicio J, de las Peas R, Vicent JM, et al. Multicenter phase Ⅰ study of irinotecan plus raltitrexed in patients with 5fluorouracilrefractory advanced colorectal cancer. Oncology, 2002, 63(1): 4247.
[14] Aparicio J, Vicent JM, Maestu I, et al. Multicenter phase Ⅱ trial evaluating a threeweekly schedule of irinotecan plus raltitrexed in patients with 5fluorouracil refractory advanced colorectal Cancer. Ann Oncol, 2003, 14(7): 11211125.
[15] 谢达成, 李宁, 王静珏, 等. 雷替曲塞联合伊立替康2周方案对比FOLFIRI方案二线治疗晚期结直肠癌的疗效观察. 临床肿瘤学杂志, 2013, 18(2): 140143.
[16] Vakhahova JV, Semenov NN, Dobrova NV, et al. Clinical study of combined use of raltitrexed and xeloda as firstline treatment for patients with metastasizing colorectal cancel. Bull Exp Biol Med, 2008, 145(2): 24925l.
[17] Garavatta L, Picardi V, Padula GD, et al. Concomitant boost radiotherapy and multidrug chemotherapy in the neoadjuvant treatment of locally advanced rectal cancer: results of a phase Ⅱ study. Acta Oncologica, 2011, 50(8): 11511157.
[18] Valentini V, Coco C, Minsky BD, et al. Randomized, multicenter, phase Ⅱb study of preoperative chemoradiotherapy in T3 middistal rectal cancer: raltitrexed + oxaliplatin + radiotherapy versus cisplatin + 5fluorouracil + radiotherapy. Int J Radiat Oncol Biol Phys, 2008, 70(2): 403412.
[19] Wilson KS, Malfair Taylor SC. Raltitrexed: optimism and reality. Expert Opin Drug Metab Toxicol, 2009, 5(11): 14471454.
[20] Kelly C, Bhuva N, Harrison M, et al. Use of raltitrexed as an alternative to 5fluorouracil and capecitabine in cancer patients with cardiac history. Eur J Cancer, 2013, 49(10): 23032310. |