国际肿瘤学杂志 ›› 2013, Vol. 40 ›› Issue (12): 933-935.doi: 10.3760/cma.j.issn.1673-422X.2013.12.017

• 综述 • 上一篇    下一篇

雷替曲塞治疗结直肠癌的临床应用

彭登付, 王勇, 胡冰   

  1. 230001 合肥,安徽医科大学附属省立医院肿瘤化疗科
  • 出版日期:2013-12-10 发布日期:2013-12-26
  • 通讯作者: 胡冰 E-mail:hubin3756@sina.com
  • 基金资助:

    安徽省自然科学基金(12070403084)

Clinical applications of raltitrexed in colorectal cancer

PENG  Deng-Fu, WANG  Yong, HU  Bing   

  1. Department of Chemotherapy, Affiliated Provincial Hospital, Anhui Medial University, Hefei 230001, China
  • Online:2013-12-10 Published:2013-12-26
  • Contact: HU Bing E-mail:hubin3756@sina.com

摘要: 雷替曲塞是一种新型的特异性胸苷酸合成酶(TS)抑制剂,在临床研究中表现出显著的抗肿瘤活性。国内外研究显示,雷替曲塞治疗结直肠癌疗效确切,耐受性较好,并且使用方便,可广泛应用于结直肠癌的临床治疗。

关键词: 结直肠肿瘤, 药物疗法, 雷替曲塞

Abstract: Raltitrexed is a specific inhibitor of thymidylate synthase (TS),  which has significant antitumor activity. Overseas and domestic researches show that raltitrexed can be widely applied in clinical treatment for colorectal cancer patients because it is effective, welltolerated and convenient.

Key words: Colorectal neoplasms, Drug therapy, Raltitrexed