Mesenchymal stem cellsbased cancer therapies

doi:10.3760/cma.j.issn.1673422X.2015.08.014

Journal of International Oncology ›› 2015, Vol. 42 ›› Issue (8): 612-615.doi: 10.3760/cma.j.issn.1673422X.2015.08.014

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Mesenchymal stem cellsbased cancer therapies

Zhang Jie, Fang Lin, Zheng Junnian

Jiangsu Key Laboratory of Biological Cancer Therapy, Xuzhou Medical College, Xuzhou 221002, China

Online:2015-08-08 Published:2015-06-29
Contact: Zheng Junnian E-mail:jnzheng@xzmc.edu.cn

Abstract

Abstract: Mesenchymal stem cells (MSCs) have inherent tumortrophic migratory properties and low immunogenicity, which allow them to serve as vehicles for delivering effective, targeted therapy to tumors. MSC plays an antitumor role by releasing some cytokines, which can be strengthened by oncolytic virus, antiangiogenesis agent, tumor necrosis factor guided apoptosis ligand, IL, IFN and prodrug. In addition, there are some advantages in combination treatment of MSC and others therapies.

Key words: Mesenchymal stem cells, Neoplasms, Vehicles

Zhang-Jie, FANG Lin, ZHENG Jun-Nian- . Mesenchymal stem cellsbased cancer therapies[J]. Journal of International Oncology, 2015, 42(8): 612-615.

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Mesenchymal stem cellsbased cancer therapies

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