Journal of International Oncology ›› 2013, Vol. 40 ›› Issue (7): 489-491.

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Parathyroid hormone related peptide and tumor 

YANG  Ming-Yan, LIANG  Hua-Sheng   

  1. Institute of Endocrine and Metabolic Diseases, Guangxi Beihai, Beihai 536000, China
  • Online:2013-07-08 Published:2013-07-08
  • Contact: LIANG Hua-Sheng E-mail:Flowchaos@yahoo.com.cn

Abstract: The parathyroid hormone related peptide (PTHrP) participates in regulating calcium and phosphorus metabolism and multiple organ growth, and plays an important role in the processes of malignant tumor bone metastasis and hypercalcemia. Currently, more and more researches have confirmed that PTHrP can be secreted by a variety of types of tumor cells. PTHrP participates in regulating tumor cell proliferation and invasion, and it is closely related to the prognosis of patients, which provides a new target of cancer treatment.

Key words: Neoplasms, Hypercalcemia, Neoplasm metastasis, Parathyroid hormone related peptide