Journal of International Oncology ›› 2013, Vol. 40 ›› Issue (6): 419-421.

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MicroRNA-203 and cancer

QI  Qiu-Feng, LIU  Yong-Ping   

  1. Department of Medicine  Oncology Laboratory, Changzhou Tumor Hospital, Changzhou 213002, China
  • Online:2013-06-08 Published:2013-05-24
  • Contact: Liu Yong-ping E-mail:liuyongping026@yahoo.com.cn

Abstract: MicroRNA(miRNA)-203 is a stemness-inhibiting miRNA that adjusts the epithelioid cell differentiation by restricting the expression of stemness-related transcription factor. Its abnormal expression has been detected in several types of human cancers, including bladder cancer, breast cancer, colon cancer and pancreatic cancer. MiRNA-203 plays a critical role in the tumor genesis and development by regulating cell proliferation, differentiation and apoptosis.

Key words: Neoplasms, MicroRNA-203, Target gene