Journal of International Oncology ›› 2013, Vol. 40 ›› Issue (5): 329-331.

Previous Articles     Next Articles

Mutual regulation of microRNA and DNA methylation in cancer

DONG  Qian-Qian, LIU  Xiao-Feng, SHANG  Rui-Lian   

  1. Department of Gastroenterology, Jinan Military General Hospital, Jinan 250031, China
  • Online:2013-05-08 Published:2013-05-15
  • Contact: Liu Xiao-feng E-mail:liuxf0531@126.com

Abstract: Both microRNA and DNA methylation are the important contents of epigenetic modification. Lots of studies have confirmed that mutual regulation of microRNA and DNA methylation involve in tumorgenesis and development of cancer. The studies of their mechanisms bring some new ideas for investigating the pathogenesis of tumors, and provide a theoretical basis for the early diagnosis and treatment.

Key words: MicroRNA, DNA methylation, Neoplasms