Journal of International Oncology ›› 2024, Vol. 51 ›› Issue (12): 779-784.doi: 10.3760/cma.j.cn371439-20240727-00132

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Research progress in the relationship between microbial communities and breast cancer in human tissues

Zhou Mingrui1, Qi Mengqi2, Zhang Yanyan1, Shi Yinuan1, Yue Chuan1, Zhang Yan1, Liu Xianqiang1, Zhang Yan1()   

  1. 1Breast Disease Diagnosis and Treatment Center, Department of Thyroid Surgery, Central Hospital Affiliated to Shandong First Medical University, Jinan 250000, China
    2Department of Geriatrics, Fourth People's Hospital of Jinan, Jinan 250000, China
  • Received:2024-07-27 Revised:2024-09-01 Online:2024-12-08 Published:2025-01-07
  • Contact: Zhang Yan E-mail:285951758@qq.com

Abstract:

Breast cancer, as a malignant tumor with a high incidence rate in women, seriously endangers the life health and safety of women. Its pathogenesis and treatment strategies are still the hot and difficult points in current research. More and more studies have shown that the occurrence and development of breast cancer is closely related to the microbial community in intestinal tissue and breast tissue, and the microbial community in human tissue may promote or inhibit the occurrence of breast cancer through various ways and mechanisms. Defining the relationship between microbial communities and breast cancer will provide new directions for the prevention and comprehensive treatment of breast cancer.

Key words: Breast neoplasms, Microbial consortia, Gastrointestinal microbiome, Lactobacillus rhamnosus