Adaptive therapy of human cancers: targeting cancer evolution

doi:10.3760/cma.j.cn371439-20191202-00038

Abstract

Abstract:

Cancer develops as result of evolution and targeting cancer evolution may be a promising cancer therapeutics. Cancer adaptive therapy is defined as targeting cancer evolution through selective adaption and co-evolution. Adaptive therapy of human cancers provides new insight into the strategies for adaption and integration through reprogramming the functions of vessel, immune, metabolism, microbiota and circadian clock, and facilitating hosts and their cancers evolution as a unit.

Key words: Neoplasms, Therapeutics, Clonal evolution

Zhang Dandan, Yue Hongyun, Zhang Baihong. Adaptive therapy of human cancers: targeting cancer evolution[J]. Journal of International Oncology, 2020, 47(6): 368-371.

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