Journal of International Oncology ›› 2019, Vol. 46 ›› Issue (9): 536-539.doi: 10.3760/cma.j.issn.1673-422X.2019.09.005

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Fructose metabolism and tumors

Zhang Zhiping, Qi Xiaofei   

  1. Department of Hematology, First Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology, Key Laboratory of Thrombosis and Hemostasis of Ministry of Health, Collaborative Innovation Center of Hematology, Institute of Blood and Marrow Transplantation, Soochow University, Suzhou 215006, China
  • Received:2019-07-22 Online:2019-09-08 Published:2019-09-08
  • Contact: Qi Xiaofei E-mail:qixiaofei@suda.edu.cn

Abstract: Increasing sugar intake can be considered as a risk factor for some tumors, such as breast cancer, lung cancer, endometrial cancer, ovarian cancer, gallbladder cancer, pancreatic cancer, etc. Fructose can promote tumor formation and progression by several mechanisms, resulting in poor prognosis and increased chemotherapy resistance. Limitation of fructose consumption can reduce the risk of tumor, delay tumor progression and improve drug resistance, playing an auxiliary role in tumor treatment.

Key words: Neoplasms, Fructose, Metabolism