Research progress on the mechanism of microRNA regulation of cisplatin resistance in ovarian cancer

doi:10.3760/cma.j.cn371439-20231109-00030

Abstract

Abstract:

Cisplatin resistance is an important factor in the poor treatment effect of ovarian cancer patients. MicroRNA （miRNA） can regulate cellular structural molecules， DNA repair， cell cycle， apoptosis and Wnt/β-catenin signaling pathway， autophagy， methylation and cancer stem cell， which are involved in the regulation of cisplatin resistance in ovarian cancer. Further understanding the mechanism of miRNA regulation of cisplatin resistance in ovarian cancer will help find new treatment options to optimize existing treatment plans and improve efficacy.

Key words: Ovarian neoplasms, MicroRNAs, Cisplatin, Drug resistance, neoplasm

Gong Yan, Chen Honglei. Research progress on the mechanism of microRNA regulation of cisplatin resistance in ovarian cancer[J]. Journal of International Oncology, 2024, 51(3): 186-190.

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