Targeted therapy and immunotherapy of esophageal cancer

doi:10.3760/cma.j.cn371439-20210520-00043

Abstract

Abstract:

Esophageal cancer is a complex digestive tract cancer. Currently, the study of radiotherapy and chemotherapy for non-surgical esophageal cancer has reached the bottleneck. In recent years, with the in-depth study of tumor signal pathway related targets and immunotherapy, tumor treatment methods are becoming more and more diversified. At present, research shows that a variety of gene targets and immune receptors are related to esophageal cancer, including epidermal growth factor receptor, vascular endothelial growth factor, human epidermal growth factor receptor 2, programmed death-1/programmed death ligand-1, etc. In addition, tumor vaccine and adoptive cell therapy are also being studied. These factors contribute to the individualized and accurate treatment of esophageal cancer and improve survival rate and local control rate.

Key words: Esophageal neoplasms, Molecular targeted therapy, Immunotherapy

Zhou Jianfeng, Wang Tiejun. Targeted therapy and immunotherapy of esophageal cancer[J]. Journal of International Oncology, 2022, 49(4): 237-242.

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