Journal of International Oncology ›› 2022, Vol. 49 ›› Issue (4): 243-246.doi: 10.3760/cma.j.cn371439-20220208-00044

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Potential value of radiotherapy combined with immunotherapy in breast cancer brain metastases

Sun Xiaolin1, Zhang Zhanyu1, Xu Linzong1, Liu Yingchao2, Li Xiaomei1()   

  1. 1Tumor Research and Therapy Center, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan 250021, China
    2Department of Neurosurgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, China
  • Received:2022-02-08 Revised:2022-03-03 Online:2022-04-08 Published:2022-05-11
  • Contact: Li Xiaomei E-mail:sdulixiaomei@163.com

Abstract:

With the increasing understanding of the unique tumor microenvironment in the brain, immunotherapy have emerged as a new and promising treatment for brain metastases. Radiotherapy and immunotherapy have a synergistic effect, and it is of great value to understand its mechanism in the treatment of breast cancer brain metastases. At present, the study of immune checkpoint inhibitors combined with radiotherapy in breast cancer brain metastases is being actively carried out, bringing new hope to patients with breast cancer brain metastases.

Key words: Breast neoplasms, Brain metastases, Immune checkpoint inhibitors, Radiotherapy