Journal of International Oncology ›› 2022, Vol. 49 ›› Issue (3): 181-184.doi: 10.3760/cma.j.cn371439-20220104-00031

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Progression of radiotherapy for brain metastases in non-small cell lung cancer

Ji Huan, Zhou Juying(), Ma Chenying, Xu Xiaoting, Qin Songbing   

  1. Department of Radiation Oncology, First Affiliated Hospitial of Soochow University, Suzhou 215006, China
  • Received:2022-01-04 Revised:2022-01-11 Online:2022-03-08 Published:2022-03-22
  • Contact: Zhou Juying E-mail:zhoujuyingsy@163.com

Abstract:

Brain metastases are one of the most common distant metastases in patients with non-small cell lung cancer (NSCLC), and the prognosis will be extremely poor. The effect of chemotherapy and operation is limited. As a standard treatment, radiotherapy is widely used in clinical practice. Radiotherapy alone includes whole brain radiotherapy, stereotactic radiotherapy and whole brain radiotherapy combined with stereotactic radiotherapy. With the continuous development of radiotherapy and the progress of gene sequencing, radiotherapy has been combined with targeted drugs, anti-angiogenic drugs and immunodrugs in the treatment of NSCLC brain metastasis, which can improve the survival of patients with NSCLC brain metastasis.

Key words: Carcinoma,non-small-cell lung, Brain metastasis, Radiotherapy, Molecular targeted therapy, Antiangiogenic therapy