M2 macrophage marker CD206 and tumor

doi:10.3760/cma.j.issn.1673-422X.2019.03.009

Abstract

Abstract: Tumorassociated macrophages exist in all stages of tumor progression, and stimulate angiogenesis and invasion of tissues. M2 macrophages are predominant. CD206 is a M2 macrophage marker with high specificity and plays an important role in tumor cell proliferation and metastasis. Studies have shown that CD206 is closely related to malignant tumors such as breast cancer, ovarian cancer, pancreatic cancer and prostate cancer. Deepening the research on CD206 has certain clinical guiding significance for expounding the formation mechanism of tumor immune microenvironment and finding more targeted drugs.

Key words: Neoplasms, M2 macrophage, CD206

Li Yue, Gao Lei, Li Hongchang, Yu Hongjie, Zhang Yong. M2 macrophage marker CD206 and tumor[J]. Journal of International Oncology, 2019, 46(3): 174-177.

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