Journal of International Oncology ›› 2013, Vol. 40 ›› Issue (5): 377-380.

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Resistance mechanisms and the countermeasures of acute leukemia

YANG  Lu-Lu, LIU  Xin   

  1. Department of Hematology, Provincial Hospital of Anhui Medical University,  Hefei 230001, China

  • Online:2013-05-08 Published:2013-05-15
  • Contact: LIU Xin E-mail:liuxinhf@yahoo.com.cn

Abstract: Acute leukemia (AL) is a malignant disease of clonal hematopoietic stem cell abnormalities. Chemotherapy is the main method for the treatment of AL, but the chemotherapy drug resistance has become a major obstacle to successful treatment. There is often a series of drug cooccurrence of drug resistance, and that is multidrug resistance.

Key words: Leukemia, Multidrug resistance-associated proteins