New research advances of long non-coding RNA in glioma

doi:10.3760/cma.j.issn.1673-422X.2020.02.007

Abstract

Abstract:

Glioma is the most common primary intracranial tumor which is essentially a polygenic abnormal disease. Long non-coding RNA (lncRNA) is a class of noncoding genes with a length of more than 200 nucleotides. LncRNA plays an important role in tumorigenesis and development by regulating the expression of tumor-related genes or related signaling pathways. The abnormally expressions of lncRNA in gliomas contribute to the diversity of glioma phenotypes. In-depth study of the potential role of abnormally expressed lncRNA in the pathogenesis and pathological grading of gliomas will provide new ideas for clinical targeted treatment of gliomas.

Key words: RNA, long noncoding, Glioma

Nan Yang, Zhong Yue. New research advances of long non-coding RNA in glioma[J]. Journal of International Oncology, 2020, 47(2): 98-102.

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